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Anti-Gqα- and G11α-Subunits, Internal (283-300) Rabbit pAb
产品性质
biological source【生物来源】 | rabbit |
Quality Level【质量水平】 | 100 |
antibody form【抗体形式】 | purified antibody |
antibody product type | primary antibodies |
clone【克隆】 | polyclonal |
form【形式】 | liquid |
does not contain【不包含】 | preservative |
species reactivity | mouse, rat, human |
manufacturer/tradename | Calbiochem® |
storage condition【储存条件】 | OK to freeze avoid repeated freeze/thaw cycles |
isotype【同位素/亚型】 | IgG |
shipped in【运输】 | wet ice |
storage temp.【储存温度】 | −70℃ |
packaging【包装】 | 50 μL in Plastic ampoule |
基本信息
General description【一般描述】 | Anti-Gqα- and G₁₁α-Subunits, Internal (283-300), rabbit polyclonal, recognizes the ~42 kDa Gqα- and the ~43 kDa G₁₁α-subunits. Validated for use in WB and neutralization studies. Protein A purified rabbit polyclonal antibody. Recognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunit proteins. Recognizes the ~42 kDa Gqα- and the ~43 kDa G11α-subunits. Does not cross-react with other G-proteins of the non-pertussis toxin-sensitive family. |
Immunogen【免疫原】 | a synthetic peptide (IMYSHLVDYFPEYDGPQR) corresponding to an internal amino acid sequence shared by human, mouse, and rat Gqα- and G₁₁α-subunits |
Application【应用】 | Immunoblotting (1:1000) Neutralization Studies (see comments) |
Warning【警告】 | Toxicity: Standard Handling (A) |
Other Notes【其他说明】 | The antibody recognizes both Gqα and G11α since they both share the internal sequence represented by the immunizing peptide. The antibody may also be useful to block receptor G protein coupling. Does not cross-react with other G proteins of the non-pertussis toxin sensitive family. Variables associated with assay conditions will dictate the proper working dilution. Wange, R.L., et al. 1991. J. Biol. Chem. 266, 11409. Pang, I-H., and Sternweis, P.C. 1990. J. Biol. Chem. 265, 18707. Strathmann, M., et al. 1989. Proc. Natl. Acad. Sci. USA86, 7407. |
Legal Information【法律信息】 | CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 1 |