广州伟伯科技有限公司
您的位置:首页 > 产品中心 > Anti-Fgr Antibody, clone SuGr-7 14F3
产品搜索:

Anti-Fgr Antibody, clone SuGr-7 14F3

产品编号:4152184
规格:clone SuGr-7 14F3, from mouse
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
4152184100 μG5350
产品别名

Anti-Fgr Antibody, clone SuGr-7 14F3

Tyrosine-protein kinase Fgr, Fgr, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, Proto-oncogene c-Fgr, p55-Fgr, p58-Fgr, p58c-Fgr

基本信息
eCl@ss
32160702
General description【一般描述】
Tyrosine-protein kinase Fgr (EC 2.7.10.2; UniProt P09769; also known as c-fgr, c-src2, c-src-2 proto-oncogene, Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, p55-Fgr, p58-Fgr, p58c-Fgr, proto-oncogene c-Fgr) is encoded by the FGR (also known as SRC2) gene (Gene ID 2268) in human. Fgr is a member of the Src family of non-receptor protein tyrosine kinases (PTKs). Fgr contains N-terminal myristylation and palmitylation sites, a PTK catalytic domain, as well as SH2 and SH3 domains mediating interactions with phosphotyrosine-containing and proline-rich motifs, respectively. Fgr is a positive regulator of mast cell activation/degranulation and is essential for IgE-mediated passive cutaneous anaphylaxis (PCA) in mice. Fgr appears to act cooperatively with Fyn in the activation of Syk and its downstream targets in a manner that is counteracted by Lyn.
Immunogen【免疫原】
Recombinant protein corresponding to human Fgr.
Application【应用】
Detect FGR using this mouse monoclonal Anti-Fgr Antibody, clone SuGr-7 14F3, Cat. No. MABS1140, validated for use in Western Blotting.
Research Category
Signaling
Research Sub Category
Signaling Neuroscience
Western Blotting Analysis: 1.0 µg/mL from a representative lot detected Fgr in 10 µg of Ramos cell lysate.
Quality【质量】
Evaluated by Western Blotting in Daudi cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Fgr in 10 µg of Daudi cell lysate.
Physical form【外形】
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified
Other Notes【其他说明】
Concentration: Please refer to lot specific datasheet.
产品性质
Quality Level【质量水平】
100
biological source【生物来源】
mouse
antibody form【抗体形式】
purified immunoglobulin
antibody product type
primary antibodies
clone【克隆】
SuGr-7 14F3, monoclonal
species reactivity
human
technique(s)
western blot: suitable
isotype【同位素/亚型】
IgG2aκ
NCBI accession no.【NCBI登记号】
NP_001036194
UniProt accession no.【UniProt登记号】
P09769
shipped in【运输】
dry ice
产品说明
Target description【目标描述】
~59 kDa observed. Uncharacterized band(s) may appear in some lysates.
Storage and Stability【储存及稳定性】
Stable for 1 year at 2-8°C from date of receipt.
Disclaimer【免责声明】
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 1
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.0093