广州伟伯科技有限公司
您的位置:首页 > 产品中心 > Anti-CKIP1 antibody produced in rabbit
产品搜索:

Anti-CKIP1 antibody produced in rabbit

产品编号:3353698
规格:affinity isolated antibody, buffered aqueous solution
包装规格:100 μG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品价格
产品编号包装单位单价(元)国内现货国外库存询价单
3353698100 μG4610
产品别名

Anti-CKIP1 antibody produced in rabbit

Anti-Casein kinase-2-interacting protein 1

Anti-Family O member 1

Anti-Leckstrin homology domain containing

Anti-PLECKHO1

基本信息
NACRES
NA.41
Immunogen【免疫原】
CKIP1 antibody was raised against an 18 amino acid peptide from near the carboxy terminus of human CKIP1.
Features and Benefits【特点和优势】
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Linkage【联系】
The action of this antibody can be blocked using blocking peptide SBP3500109.
Physical form【外形】
Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
产品性质
biological source【生物来源】
rabbit
conjugate【偶联物】
unconjugated
antibody form【抗体形式】
affinity isolated antibody
antibody product type
primary antibodies
clone【克隆】
polyclonal
form【形式】
buffered aqueous solution
species reactivity
mouse, human, rat
technique(s)
indirect ELISA: suitable
western blot: suitable
NCBI accession no.【NCBI登记号】
NP_057358
UniProt accession no.【UniProt登记号】
Q53GL0
shipped in【运输】
dry ice
storage temp.【储存温度】
−20℃
Gene Information
human ... PLEKHO1(51177)
产品说明
Target description【目标描述】
CKIP1 was identified through a yeast-two hybrid screening as a protein that would interact with only one of the two catalytic subunits of the casein kinase 2 complex. CKIP1 is a pleckstrin homology domain-containing protein localized within the nucleus and at the plasma membrane that interacts with CK2alpha but not CK2alpha′, and is thought to play a role in targeting CK2alpha to a particular cellular location. CKIP1 has been implicated in muscle differentiation and the regulation of cell morphology and actin cytoskeleton. CKIP1 can also interact with other proteins such as ATM, an upstream kinase of p53, and recruit the nuclear ATM to the plasma membrane, suggesting CKIP1 may regulate ATM function through re-localizing ATM. CKIP1 can also form a complex with the kinase AKT, leading to a down-regulation of PI3K/AKT signaling and suppression of tumor growth in vivo.
安全信息
Storage Class Code【储存分类代码】
12 - Non Combustible Liquids
WGK
WGK 2
广州伟伯科技有限公司 版权所有 CopyRight ©2006-2024, All Rights Reserved
工信部备案号:粤ICP备08114744号   Page Run Time: 0.0209