5-甲氧基-2-甲基-3-吲哚乙酸

C₁₂H₁₃NO₃

219.24

220-734-7

MFCD00005618

24846692

NA.22

5-Methoxy-2-methyl-3-indoleacetic acid is hydrolysis product of indomethacin.

5-Methoxy-2-methyl-3-indoleacetic acid was used for quantitative determination of indomethacin and its major impurities in suppository and capsule formulations by HPLC. 5-Methoxy-2-methyl-3-indoleacetic acid was used in a study to develop fast, sensitive and simultaneous determination of metabolites of serotonin using liquid chromatography with mass spectrometric detection.

• Reactant for preparation of antimalarial agents
• Reactant for preparation of ndomethacin analogs as cyclooxygenase and lipoxygenase inhibitors with antiinflammatory activity
• Reactant for preparation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents
• Reactant for preparation of histone deacetylase inhibitors
• Reactant for preparation of 2,N6,5′-substituted adenosine derivatives as ligands for A2B adenosine receptor
• Reactant for preparation of prostaglandin D2 receptor antagonist

100

98%

161-163 ℃ (lit.)

methanol: soluble

COc1ccc2[nH]c(C)c(CC(O)=O)c2c1

1S/C12H13NO3/c1-7-9(6-12(14)15)10-5-8(16-2)3-4-11(10)13-7/h3-5,13H,6H2,1-2H3,(H,14,15)

TXWGINUZLBAKDF-UHFFFAOYSA-N

1, 5 g in glass bottle

13 - Non Combustible Solids

WGK 3

Eyeshields, Gloves, type N95 (US)