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(-)-trans-(1S,2S)-U-50488 hydrochloride hydrate
| 产品编号： | 3300706 |
| 规格： | solid, ≥98% (HPLC) |
| CAS NO： | 114528-79-9 |
| 包装规格： | 5 MG，25 MG，100 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
114528-79-9
(-)-trans-(1S,2S)-U-50488 hydrochloride hydrate
trans-(1S,2S)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)cyclohexyl]benzeneacetamide hydrochloride hydrate
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C19H26Cl2N2O · HCl · xH2O |
| Molecular weight | 405.79 (anhydrous basis) |
| MDL number | MFCD11044455 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278019 |
| NACRES | NA.77 |
| Application【应用】 | (−)-trans-(1S,2S)-U-50488 hydrochloride hydrate (U-50488) has been used as a κ-opioid receptor (KOR) agonist has been used to study its effect on the increase of tidal volumes in adult red-eared slider turtles (Trachemys scripta). |
| Biochem/physiol Actions【生化/生理作用】 | Potent κ opioid receptor agonist; more potent enantiomer of (±)-trans-U-50488. |
| Preparation Note【制备说明】 | (−)-trans-(1S,2S)-U-50488 hydrochloride hydrate is soluble in water at 13 mg/ml. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | solid |
| optical activity【旋光性】 | [α]22/D -39.0 to -32.0°, c = 0.5 in methanol(lit.) |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white |
| solubility【溶解性】 | H2O: 13 mg/mL |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | O.Cl.CN([C@H]1CCCC[C@@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3 |
| InChI | 1S/C19H26Cl2N2O.ClH.H2O/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23;;/h8-9,12,17-18H,2-7,10-11,13H2,1H3;1H;1H2/t17-,18-;;/m0../s1 |
| InChI key | UWPRPWMHQDPOFR-MPGISEFESA-N |
| Gene Information | human ... OPRK1(4986) |
| packaging【包装】 | 5, 25, 100 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
