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GLYX-13 trifluoroacetate

产品编号:3091797
规格:≥98% (HPLC)
CAS NO:117928-94-6
包装规格:1 MG
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
30917971 MG2300
产品别名

117928-94-6

GLYX-13 trifluoroacetate

TPPT-amide trifluoroacetate

Rapastinel

L-Threonyl-L-prolyl-L-prolyl-L-threoninamide trifluoroacetate; Thr-Pro-Pro-Thr-NH2 trifluoroacetate

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C18H31N5O6 · xC2HF3O2
Molecular weight
413.47 (free base basis)
MDL number
MFCD20527320
PubChem Substance ID【PubChem化学物质编号】
329825164
NACRES
NA.77
Application【应用】
GLYX-13 trifluoroacetate has been used as an activator of NMDA (N-methyl-D-aspartate) receptor.
Biochem/physiol Actions【生化/生理作用】
GLYX-13 is a glycine-site functional partial agonist (GFPA) selective modulator of the NMDA receptor (NMDAR). It is a brain penetrable tetrapeptide which acts as a positive allosteric modulator of the NMDA receptor, acting via the glycine site. GLYX-13 has been found to be a cognitive enhancer in learning models and is currently in clinical trials as an antidepressant.
产品性质
Quality Level【质量水平】
100
Assay【测定】
≥98% (HPLC)
form【形式】
powder
color【颜色】
white to tan
shipped in【运输】
wet ice
storage temp.【储存温度】
−20℃
SMILES string
OC(=O)C(F)(F)F.C[C@@H](O)[C@H](N)C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)N[C@@H]([C@@H](C)O)C(N)=O
InChI
1S/C18H31N5O6.C2HF3O2/c1-9(24)13(19)18(29)23-8-4-6-12(23)17(28)22-7-3-5-11(22)16(27)21-14(10(2)25)15(20)26;3-2(4,5)1(6)7/h9-14,24-25H,3-8,19H2,1-2H3,(H2,20,26)(H,21,27);(H,6,7)/t9-,10-,11+,12+,13+,14+;/m1./s1
InChI key
BCWVNVCGYWOAAK-GDLIIDCZSA-N
packaging【包装】
1 mg in glass bottle
安全信息
Storage Class Code【储存分类代码】
13 - Non Combustible Solids
WGK
WGK 3
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