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γ-氨基丁酸

γ-Aminobutyric acid
产品编号:3089745
规格:BioXtra, ≥99%
CAS NO:56-12-2
包装规格:10 G,25 G,100 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
308974510 G816
308974525 G1630
3089745100 G3270
产品别名

56-12-2

γ-氨基丁酸

γ-Aminobutyric acid

3-Carboxypropylamine

GABA

Piperidinic acid

4-Aminobutanoic acid

Piperidic acid

4-氨基丁酸

氨酪酸

3-羧丙胺

哌啶酸

结构式
基本信息
Linear Formula【线性分子式】
NH2(CH2)3COOH
Molecular weight
103.12
Beilstein
906818
EC number【EC 号】
200-258-6
MDL number
MFCD00008226
PubChem Substance ID【PubChem化学物质编号】
24891025
NACRES
NA.26
General description【一般描述】
γ-Aminobutyric acid (GABA) is a non-protein amino acid associated with the brain. Being synthesized in the nervous system, it is packed into synaptic vesicles. It is present naturally in green tea, soybean, germinated rice, and in some fermented foods.
Application【应用】
γ-Aminobutyric acid (GABA) has been used to treat dorsal root ganglion neurons for electrophysiological recordings studies to test its effect on neuropathic pain in rats. It has also been used to test its protective effects in an ex vivo machine perfusion system of small-for-size grafts (SFSG) injury model.
Biochem/physiol Actions【生化/生理作用】
γ-Aminobutyric acid (GABA) is a mammalian inhibitory neurotransmitter with multiple functions. It is crucial for the normal central nervous system (CNS) functioning. A few documented functions of GABA include its protective role in toxin-induced damage. It also elicits anti-hypertensive, anti-diabetic, anti-microbial, antioxidant, anti-allergy, anti-inflammatory, and anti-cancer effects. GABA might show beneficial effects on stress and sleep in humans. γ-Aminobutyric acid (GABA) is used to study the biological and biochemical processes mediated via the GABA receptors, GABAA and GABAB.
大脑中的主要抑制性神经递质;GABAA 和 GABAB 受体激动剂;增加 Cl 的传导性。
产品性质
Quality Level【质量水平】
200
product line【产品线】
BioXtra
Assay【测定】
≥99%
form【形式】
powder
technique(s)
ligand binding assay: suitable
impurities【杂质】
<0.0005% Phosphorus (P)
<0.1% Insoluble matter
ign. residue【灼烧残渣】
<0.1%
color【颜色】
white
mp
195 ℃ (dec.) (lit.)
solubility【溶解性】
H2O: 0.5 M at 20 ℃, clear, colorless
anion traces【痕量阴离子】
chloride (Cl-): <0.04%
sulfate (SO42-): <0.05%
cation traces【痕量阳离子】
Al: <5 mg/kg
Ca: <20 mg/kg
Cu: <5 mg/kg
Fe: <5 mg/kg
K: <50 mg/kg
Mg: <50 mg/kg
NH4+: <500 mg/kg
Na: <70 mg/kg
Pb: <10 mg/kg
Zn: <5 mg/kg
SMILES string
NCCCC(O)=O
InChI
1S/C4H9NO2/c5-3-1-2-4(6)7/h1-3,5H2,(H,6,7)
InChI key
BTCSSZJGUNDROE-UHFFFAOYSA-N
Gene Information
human ... SLC6A1(6529), SLC6A11(6538), SLC6A12(6539)
rat ... Gabra1(29705), Gabra2(29706), Olr1750(294204), Slc6a1(79212), Slc6a12(50676)
packaging【包装】
10 mg in autosample vial
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
dust mask type N95 (US), Eyeshields, Gloves
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